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The study focuses on the study of human subcutaneous white adipose tissue heterogeneity using single-cell and spatial omics technologies, including single-cell RNA sequencing (scRNA-seq), single-nucleus RNA sequencing (snRNA-seq), bulk RNA sequencing, proteomic analysis, lipidomic analysis, and metabolomic analysis, to provide innovative biomarkers for identifying rare progenitor cell subpopulations and accurately defining lineage hierarchy and differentiation status. These studies have the potential to support reproducible and effective clinical applications using adipose tissue derivatives for regenerative medicine purposes.

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This page is a summary of: Dissecting human adipose tissue heterogeneity using single‐cell omics technologies, Stem Cell Research & Therapy, September 2024, Springer Science + Business Media,
DOI: 10.1186/s13287-024-03931-w.
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