What is it about?
Trial comparing balanced fluids with saline in diabetic ketoacidosis
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Why is it important?
The incidence of new or progressive AKI and resolution of AKI were similar in both groups. Plasma-Lyte-A was similar to 0.9% Saline in time to resolution of DKA, need for RRT, mortality, and lengths of PICU and hospital stay.
Perspectives
Larger trials are needed to prove the role of balanced fluids in diabetic ketoacidosis
Vijai Williams
Postgraduate Institute of Medical Education and Research, India
Read the Original
This page is a summary of: 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial, Critical Care, January 2020, Springer Science + Business Media,
DOI: 10.1186/s13054-019-2683-3.
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