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Authors identify the SMC1A gene as decisive player in the cascade of events leading to the transformation of the intestinal mucosa from healthy to cancerous. Furthermore, SMC1A could be used as indicator of tumor progression. Finally, in the future, the SMC1A-encoded protein could become a target of new colorectal cancer therapies.
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This page is a summary of: Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development, Journal of Experimental & Clinical Cancer Research, March 2019, Springer Science + Business Media,
DOI: 10.1186/s13046-019-1116-0.
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L'amplificazione del gene SMC1A contribuisce allo sviluppo del tumore del colon-retto
Comunicato stampa - I risultati di uno studio coordinato dall’Istituto di ricerca genetica e biomedica del Cnr, pubblicati sul Journal of Experimental & Clinical Cancer Research, hanno identificato un nuovo meccanismo molecolare coinvolto nello sviluppo del tumore del colon-retto. Lo studio potrebbe aprire la strada a terapie mirate
Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development
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