Toward precision medicine of breast cancer

What is it about?

This report is an extensive review on breast cancer that covers (i) incidence and prevention, (ii) mammary gland complexity and cell type diagnosis, (iii) carcinogenesis process and consequences for patients, (iii) consequence of tumor heterogeneity on cancer evolution and drug resistance, (iv) hallmarks of cancer, (v) molecular targets for breast cancer treatments, (vi) drug therapy, (vii) hormone therapy, (viii) immunotherapy, (ix) nanoparticle therapy, (x) high throughput technologies to assist precision therapies, (xi) genome sequencing, (xii) transcriptome profiling, (xiii) proteome profiling, (xiv) network modeling, (xv) gene regulatory networks, (xvi) protein-protein interactome, (xvii) relationship between disease and protein networks, (xviii) characterization of protein targets, (xi) challenges of precision therapy, (xx) molecular and physiological effects of drugs in precision therapies, and (xxi) engineering precision therapies.

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Why is it important?

The comprehensive coverage of this study is important because it gives a complete view of the problem.

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