What is it about?
PTSD is a famous mental disease, but it also derives secondary symptom, e.g., heart disease. It is not known what mediates it.
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Why is it important?
Integrated analysis of mRNA and miRNA, we identified critical mRNAs/mRNAs that mediates PTSD mediated heart failure.
Perspectives
As a bioinformatics researcher, it is an application of PCA based unsupervised FE, which I have recently proposed. For this methodology, see https://www.researchgate.net/project/Principal-Component-Analysis-based-unsupervised-Feature-extraction
Professor Y-h. Taguchi
Chuo Daigaku
Read the Original
This page is a summary of: Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease, BMC Bioinformatics, April 2015, Springer Science + Business Media,
DOI: 10.1186/s12859-015-0574-4.
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