What is it about?
plasma bile acids can activate TGR5 and BAT activity in mice but in human it seems more difficult at least when kidney disease is involved
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Why is it important?
shows for the first time that human with high bile acids circulating which should actibvate TGR5 do not have more energy expenditure
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This page is a summary of: Plasma bile acids are not associated with energy metabolism in humans, Nutrition & Metabolism, January 2010, Springer Science + Business Media,
DOI: 10.1186/1743-7075-7-73.
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