What is it about?
DNA replication is under the control by an unkown mechanism. Here we established genetic links between several genes of the central carbon metabolism and the initiator of DNA replication DnaA.
Featured Image
Why is it important?
Central carbon metabolism and DNA replication are two ubiquitous, essential processes. Here we found genetic links between metabolic and replication genes in the bacterium Escherichia coli. Similar links were found in another bacterium (Bacillus subtilis that diverged from E coli 1 billion years ago), in the backer yeast and in higher eukaryotes. We thus propose that these links are ubiquitous in living organisms.
Read the Original
This page is a summary of: Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli, Microbial Cell Factories, January 2011, Springer Science + Business Media,
DOI: 10.1186/1475-2859-10-19.
You can read the full text:
Contributors
The following have contributed to this page
