What is it about?

Analysis of eukaryotic gene expression profiles during Shigella infection in the presence and absence of an apoptosis inducer.

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Why is it important?

Shigella inhibits apoptosis or cell death in epithelial cells. This analysis demonstrates how Shigella infection results in an induced pro-survival state of epithelial cells, which enables Shigella to establish a replicative niche inside the host.

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This page is a summary of: Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition, BMC Genomics, April 2010, Springer Science + Business Media,
DOI: 10.1186/1471-2164-11-272.
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