Identification of near-native protein conformations among 3D docked models

What is it about?

Despite progress in docking techniques, those methods produce a large number of putative models. The identification of the best one is addressed in this article.

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Why is it important?

Since proteins function by interacting with other molecules, analysis of protein-protein interactions is essential for comprehending biological processes. Whereas understanding of atomic interactions within a complex is especially useful for drug design, limitations of experimental techniques have restricted their practical use. Consequently, there is a need of producing accurate computational techniques.