Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia

What is it about?

Chronic intermittent hypoxia (IH), a hallmark characteristic of obstructive sleep apnea, induces significant cognitive deficits in mice, the reversibility of which is unclear. Here, we show that there are temporally dependent adverse effects of IH on performance and recovery using a novel object recognition task. Thus, the longer the disease goes undiagnosed and untreated, the less likely cognitive functional recovery will occur.

Featured Image