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Mast cells released chymase-1 (CMA1) induces macrophages to produce TNF-alpha in the lung and promotes the pathogenesis of chronic obstructive pulmonary disease (COPD). Targeting CMA1 may be a novel therapeutic option to COPD

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This page is a summary of: Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease, European Respiratory Journal, July 2022, European Respiratory Society (ERS),
DOI: 10.1183/13993003.01431-2021.
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