What is it about?
The aims of this review are: 1. To review the major physiological changes in biochemical tests in normal pregnancy. 2. To outline where these physiological changes are important in interpreting laboratory investigations in pregnancy. 3. To document the most common causes of abnormalities in biochemical tests in pregnancy, as well as important pregnancy-specific causes.
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Why is it important?
Interpretation of laboratory investigations relies on reference intervals. Physiological changes in pregnancy may result in significant changes in normal values for many biochemical assays, and as such results may be misinterpreted as abnormal or mask a pathological state.
Perspectives
I hope this article aids in the timely diagnosis of pathological conditions and in minimising misdiagnoses in pregnancy.
Dr Stephanie Louise Teasdale
Mater Hospital Brisbane
Read the Original
This page is a summary of: Changes in biochemical tests in pregnancy and their clinical significance, Obstetric Medicine, May 2018, SAGE Publications,
DOI: 10.1177/1753495x18766170.
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