What is it about?

In this paper we show that two novel inflammatory biomarkers, blood count of CD45-positive platelets and neutrophil to lymphocyte ratio, are elevated in patients with coronary artery disease and type 2 diabetes mellitus, who developed in-stent restenosis during the first year after drug-eluting stent implantation.

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Why is it important?

This is significant because in-stent restenosis after drug-eluting stent implantation remains an important adverse outcome of coronary angioplasty. The possibility to predict and prevent restenosis can improve results of coronary artery stenting.

Perspectives

We built a logit regression model, which showed that the combination of 3 factors (namely: CD45-positive platelets, neutrophil to lymphocyte ratio and diabetes mellitus) possess the higher ability to predict restenosis occurrence, than those factors, taken separately.

Zufar Gabbasov
Institute of Experimental Cardiology Cardiology Research Center

Read the Original

This page is a summary of: Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease, Clinical and Applied Thrombosis/Hemostasis, May 2018, SAGE Publications,
DOI: 10.1177/1076029618771752.
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