What is it about?

Multiple myeloma is characterized by bone-pain, pathologic fractures, hypercalcemia. Patients with MM have a worse health-related quality of life than patients with other hematologic diseases

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Why is it important?

In this study, we found that multiple myeloma subjects showed high scores in HRQoL scales, approximately 11 points higher than those observed in reference studies. In our sample, the score was under 50 points (0-100 scales by linear transformation), and represents a low level of symptoms. Until now, the current data are the only report on this issue in the western region of Mexico. We found that renal failure is related significantly with high scores in fatigue, pain, and insomnia scales. Hypercalcemia was associated significantly with global health status/QoL. Symptoms scales are related to age, renal damage, disease-free survival. We observed a correlation among global health status/QoL, general satisfaction, and treatment schedules.

Perspectives

Identification of markers that are related to the quality of life in patients with MM, such as pain, fatigue, anemia, and renal failure is pivotal, as it indicates the need to be persistent in the relevant therapeutic intervention aimed at modifying these markers to improve quality of life. A good quality of life is related to overall survival. Identifying the level of satisfaction of care in these patients that correlates with markers of tumor burden allows us to anticipate the efficacy and opportunity of treatment, and early intervention will improve the perception of care in health services.

benjamin rubio-Jurado
INSTITUTO MEXICANO DEL SEGURO SOCIAL

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This page is a summary of: Health-Related Quality of Life and Satisfaction With Health Care: Relation to Clinical Stage in Mexican Patients With Multiple Myeloma, Cancer Control, January 2019, SAGE Publications,
DOI: 10.1177/1073274819831281.
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