What is it about?
Heart failure (HF) is a leading cause of hospitalization across the world and is known to cause ill-health and heavy economic losses. Fenofibrate treatment protected the heart against chronic heart failure in rats.
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Why is it important?
The study for the first time demonstrates the ability of fenofibrate to ameliorate the baroreflex sensitivity along with ventricular functions,ECG alterations, and ventricular hypertrophy in ISO-induced HF in Wistar rats.
Perspectives
The present study highlights how the correction of cardiac energy metabolism protects the heart from damage and will give a larger window period to patients
swati omanwar
Indira Gandhi National Open University
Read the Original
This page is a summary of: Fenofibrate ameliorates neural, mechanical, chemical, and electrical alterations in the murine model of heart failure, Human & Experimental Toxicology, June 2019, SAGE Publications,
DOI: 10.1177/0960327119860173.
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