What is it about?
This is the first study, to the authors’ knowledge, to identify serum reactivity to a purified hot saline extract SBPPS of B. melitensis in ovine brucellosis. Moreover, we have developed a simple and rapid screen field test for the serodiagnosis of sheep brucellosis, LAT, using SBPPS of B. melitensis as antigen.
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Why is it important?
The developed test may be suitable for use in the field as (i) it is very easy to perform and to read, (ii) it does not require expensive equipment and electricity, (iii) it does not require access to a diagnostic laboratory and can be used in places where there is no access to veterinary care, and (iv) it is as sensitive and specific as the four other validated tests.
Perspectives
The identification of protein components of Brucella that elicit an antibody response in the majority of infected animals would improve the diagnosis of the disease and contribute to the development of new vaccine strategies. Hence, further studies will needed to evaluate the SBPPs of B. melitensis as vaccine candidate using the safe molecular methods.
Assoc. Prof. Alaa B. Ismael
Medical sciencesFaculty of Applied Medical Sciences, Taif University, Turrabah
Read the Original
This page is a summary of: Latex agglutination using the periplasmic proteins antigen of Brucella melitensis is a successful, rapid, and specific serodiagnostic test for ovine brucellosis, International Journal of Immunopathology and Pharmacology, July 2016, SAGE Publications,
DOI: 10.1177/0394632016648709.
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