What is it about?
Cannabinoids are drugs of abuse able to lead to aberrant forms of limbic- emotional-memory. In this research we showed for the first time by the EOR test that preconditioning administration of a CB receptor agonist potentiates the association of a positive emotional experience with a neutral cue. When administered after the reward-conditioning, memory of the same association is weakened.
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Why is it important?
Our evidence is fundamental in proving that cannabinoid activation represents a condition that reinforces the encoding and retrieval of subsequent positive emotional experiences, prioritises information in memory according to value attribution and decreases the formation of aversive limbic memory.
Perspectives
I am really glad for this publication that took much t to me and my co-authors. I deeply believed in these results and now I hope that many researchers can enjoy this manuscript!
Carla Cannizzaro
University of Palermo, Italy
Read the Original
This page is a summary of: Reward-related limbic memory and stimulation of the cannabinoid system: An upgrade in value attribution?, Journal of Psychopharmacology, September 2017, SAGE Publications,
DOI: 10.1177/0269881117725683.
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