Hypoxia in Atherogenesis

What is it about?

It has been shown that atherosclerosis is associated with hypoxia in some regions of the artery wall. This is associated with some profound changes in cell function. These changes may be involved in plaque progression and may have implications for therapeutic interventions.

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Why is it important?

This review provides an update of some new findings in this area of vascular biology. The role of HIFs may be important during the early stages of vascular disease.