What is it about?
Positive signs are clinical signs considered the hallmark of functional neurological disorders. Among patients with headache but without a known functional neurological disorder, positive signs are frequently encountered, mostly unnoticed by the patient. Headache patients with positive signs report more severe headache condition than headache patients without positive signs.
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Why is it important?
Our findings point positive signs as part of the clinical spectrum of headache. They also identified a clinical marker of headache severity, supporting clinicians to adopt a more intensive therapy for headache patients with these signs.
Perspectives
The presence and significance of positive signs -the hallmark of functional neurological disorders- among patients without functional neurological disorders opens new insights in the pathophysiology beyond the actual definition of functional neurological disorders.
Eric Morel
Centre Hospitalier Universitaire Vaudois
Read the Original
This page is a summary of: Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study, Journal of Neuropsychiatry, June 2025, American Psychiatric Association,
DOI: 10.1176/appi.neuropsych.20250004.
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