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Among individuals who engaged in regular cannabis use and heavy episodic drinking, smoked cannabis induced acute increases in subjective intoxication, affect, arousal, cardiovascular effects, blood THC concentrations, and acutely reduced alcohol consumption without a consistent effect on alcohol craving.

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This page is a summary of: Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial, American Journal of Psychiatry, November 2025, American Psychiatric Association,
DOI: 10.1176/appi.ajp.20250115.
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