What is it about?
This article describes the evidence for upregulation of the NFKB pathway in pteryigum
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Why is it important?
The NFkB pathway is a commom proinflammatory pathway involved in tumor formation and immune dysfunction. If NFKB is involved in pteryigum, there may be a way to treat it based on existing drugs that target this pathway.
Perspectives
NF kB inhibitors are already available in oncology. Perhaps repurposing of some of these drugs and injected locally into the pterygium can be a non surgical treatment, or an adjunct to cases with higher risk of recurrence.
Prof Louis Tong
National University of Singapore
Read the Original
This page is a summary of: The Nuclear-Factor κB Pathway Is Activated in Pterygium, Investigative Ophthalmology & Visual Science, January 2011, Association for Research in Vision and Ophthalmology (ARVO),
DOI: 10.1167/iovs.10-5735.
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