Automated Parenchymal Pattern Analysis of Treatment Responses in Pulmonary Alveolar Proteinosis

What is it about?

Computer-Aided Lung Informatics for Pathology Evaluation and Rating (CALIPER) software provides an unsupervised algorithm to quantify specific lung parenchymal patterns (normal lung, hyperlucent, ground-glass opacification, reticular, honeycombing, and pulmonary vessels) using digital chest CT data. Here we use CALIPER to quantify the relative therapeutic responses to whole lung lavage and inhaled GM-CSF therapy in a patient with autoimmune pulmonary alveolar proteinosis.

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