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Progressive lung damage is a hallmark of cystic fibrosis (CF). We show that lung damage in CF infants associates with the active release of toxic mediators by a type of inflammatory cells called neutrophils, opening avenues for early therapy.
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This page is a summary of: Elastase Exocytosis by Airway Neutrophils Is Associated with Early Lung Damage in Children with Cystic Fibrosis, American Journal of Respiratory and Critical Care Medicine, April 2019, American Thoracic Society,
DOI: 10.1164/rccm.201803-0442oc.
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