Genetic alterations that influence the evolution of colon cancer.

What is it about?

To present the case of a patient with colon cancer in two different sites of the same and his genetic study to determine his best treatment. Highlight the importance of joint management of patients with colon cancer to obtain the best results and post-surgical follow-up. Choose the best adjuvant therapy and be able to improve the survival and quality of life of the patient. Through the presentation of this case, we seek to disseminate the importance of carrying out and reporting the genetic alterations found in the surgical piece with the aim of determining the best target therapy, in addition to promoting the relationship between the various specialists involved in the management of the colon cancer to lay the foundations for studies with more clinical cases and greater statistical power and thus reinforce the knowledge found. It is important to emphasize that most pathology reports do not include all the information contained in this case and that is why we undertook the task of doing so, to highlight the importance of an increasingly complete and detailed report and its influence. in the knowledge of the surgeon in the biology of the tumor and its evolution. Other centers are urged to search for these alterations in their surgical specimens in order to carry out larger and multicenter studies, in order to increase knowledge about microsallettal instabilities and their impact on the evolution and development of the patient's disease, as well as their treatment before and after having undergone surgery. We hope it will be of interest to you.

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Photo by National Cancer Institute on Unsplash

Photo by National Cancer Institute on Unsplash

Why is it important?

Knowing the genetic alterations involved in the development of cancer supports the medical oncologist which therapy to use and which is more effective to prevent recurrence.

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