What is it about?
This is a series of cases of fresh and large bleeding under the retina, something that can lead to blindness, treated with a new anti-VEGF drug named Brolucizumab and SF6 gas. We did not use RTPA which is expensive and often not available at small, private practice! We also didn't do any surgeries. All our cases recovered well both in terms of vision and clearance of the blood.
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Photo by Harpreet Singh on Unsplash
Why is it important?
Bleeding under the retina can lead to blindness. It is not uncommon. More so in Asiatic population where we commonly get PCVs. A non surgical approach based on Brolucizumab injection and SF6 gas can be easily replicated in the real world. This is the first report of such an approach. Also we achieved these outcomes without using a loading dose of the ANTI-VEGF!
Perspectives
I often get patients with massive subretinal bleed. I find surgery in these cases technically demanding. A medical approach that too, without using RTPA which is expensive and not easily available to independent retina practice like mine, is really a great help. Brolucizumab appears to be a safe and effective drug in this situation. It helps resolve both the cause (the PCV) and the effect (sub retinal bleed)
Somnath Chakraborty
Retina institute of Bengal
Read the Original
This page is a summary of: Management of Submacular Hemorrhage Using Intravitreal Brolucizumab with Pneumatic Displacement: A Case Series, Case Reports in Ophthalmology, November 2022, Karger Publishers,
DOI: 10.1159/000527073.
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