What is it about?
Eosinophilic colitis and hypereosinophilic syndrome with colic involvement are rare diagnosis that are characterized by wide-ranging gastrointestinal symptoms and idiopathic infiltration of eosinophils in the colon. The diagnostic workup is challenging since there are no standardized criteria. We report a case of a man admitted to the hospital with a history of nonbloody chronic diarrhea. This case report describes the diagnostic workup and highlights the most important features of this often underdiagnosed entity.
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Why is it important?
Eosinophilic Colitis is a rare gastrointestinal disease and the least frequent manifestation of primary eosinophilic gastrointestinal disorders. The presentation of this case demonstrates that, although Eosinophilic Colitis is a rare disease, it is essential that we perform a detailed clinical history to identify or exclude an atopic background and dismiss other possible causes of hypereosinophilia. The histopathological examination is essential, despite the lack of diagnostic criteria and clear cut-offs. The treatment decision should always be discussed, and the clinical response must be monitored closely to promptly identify refractory patients that may need subsequent treatment with other pharmacological targets.
Perspectives
Eosinophilic Colitis is a rare disorder that it is not easy to diagnose and has no standard treatment. In this case report, we describe the diagnosis workup and a treatment approach that allowed clinical improvement of this patient.
Pedro Cardoso
Hospital São João
Read the Original
This page is a summary of: Eosinophilic Colitis, an Uncommon Cause of Diarrhea: Case Report and Literature Review, GE - Portuguese Journal of Gastroenterology, December 2022, Karger Publishers,
DOI: 10.1159/000526853.
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