What is it about?

Malaria is life-threatening protozoan infection usually detriment in children below 5yrs. The study assessed the stress and hematological levels of complicated and uncomplicated malaria in children in Ghana and how an antioxidant like Vitamin C supplementation can help in reducing oxidative stress and help improve malaria treatment.

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Why is it important?

Malaria is known to have detrimental effects on several biochemical features or parameters in the body. Some of which are glutathione levels, catalase levels, creatinine levels, malondialdehyde (MDA) content and others. This study placed utmost importance on the MDA levels as well as vitamin C levels. These parameters were chosen since MDA is perfect for predicting malaria disease progression and at the same time vitamin C is a very important antioxidant especially in children. This study established decreased vitamin C contents in the severely ill malaria patients but increased MDA levels in them.

Perspectives

This work placed much emphasis on derangements in children. Children were considered because they suffer most during malaria attack as a result of their weak immune system. Hence an antioxidant linked to the immune system like vitamin C content was analysed in the study. It was a great pleasure writing this article knowing the positive effects it will have on policy formulation particularly in malaria endemic areas.

Bernard Bahaah Akwasi Efa
Kwame Nkrumah University of Science and Technology

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This page is a summary of: Oxidative Stress and Hemoglobin Level of Complicated and Uncomplicated Malaria Cases among Children: A Cross-Sectional Study in Kumasi Metropolis, Ghana, Journal of Tropical Medicine, July 2019, Hindawi Publishing Corporation,
DOI: 10.1155/2019/8479076.
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