What is it about?
The expression of CSF-1 is a potential prognostic marker for predicting patient survival and recurrence in UTUC.
Featured Image
Why is it important?
We offered the first evidence that high CSF-1 expression is a potential prognostic marker for predicting patient survival and recurrence of UTUC. First, the expression of CSF-1 was higher in UTUC tissues than in cancer-adjacent normal tissues. Second, positive staining of CSF-1 was mainly expressed in the nucleus. Third, a high level of CSF-1 positively correlated with tumor stage, tumor size, distant metastasis, and recurrence. Finally, CSF-1 expression was associated with poor disease-free and cancer-specific survival, and univariate and multivariate proportional hazard analyses indicated that it was also an independent prognostic biomarker for patients with UTUC.
Perspectives
We hope our results will help determine the prognosis for UTUC patients and may also help indicate a plan for aggressive treatment.
WEI CHI HSU
Kaohsiung Medical University
Read the Original
This page is a summary of: CSF-1 Overexpression Predicts Poor Prognosis in Upper Tract Urothelial Carcinomas, Disease Markers, August 2019, Hindawi Publishing Corporation,
DOI: 10.1155/2019/2724948.
You can read the full text:
Contributors
The following have contributed to this page
