What is it about?

People living with HIV/AIDS have cognitive deficits of different intensities, with the dementia associated with HIV being the most serious of them. Physical exercise programs and nutritional modulation have been investigated in isolation and/or in combination lately, in order to reduce or even prevent the progression of damage caused by different types of dementia in different populations. Specifically, the model of resistance training has been shown to be able to change the path of cognitive and motor decline, even after a single training session. It has been shown that the serum glutamine concentration in people with HIV reach a reduction of about 40%−50% due to the accelerated metabolism of the immune system cells. Some authors have investigated the hypothesis of glutamine involvement in brain functions, making the key role of this amino acid in the CNS metabolism clear. Thus, the glutamine supplementation and resistance training together may provide a big improve in cognition.

Featured Image

Why is it important?

This study demonstrated that glutamine supplementation may increase the benefits that exercise promote in cognition of people living with HIV/AIDS

Perspectives

This paper is designed to demonstrate a potential benefit of physical exercise associated with nutritional strategies in conditions that cause loss of muscle mass, such as HIV

PhD Ademar Avelar
Universidade Estadual de Maringá

Read the Original

This page is a summary of: The Effect of a Short Period of Supplementation with Glutamine Dipeptide on the Cognitive Responses after a Resistance Training Session of Women with HIV/AIDS: A Randomized Double-Blind Placebo-Controlled Crossover Study, BioMed Research International, January 2018, Hindawi Publishing Corporation,
DOI: 10.1155/2018/2525670.
You can read the full text:

Read
Open access logo

Resources

Contributors

The following have contributed to this page