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This paper examines the role of extracellular vesicles (EVs) in regenerative medicine, focusing on their potential to treat degenerative diseases. Current research indicates that intravenously administered EVs are primarily sequestered in the liver, spleen, and lungs. To optimize therapeutic efficacy and minimize off-target effects, recent studies are exploring diverse bioengineering strategies to enhance tissue-specific targeting. Authors review the existing strategies for in vivo tracking and targeting of EVs isolated from different cellular sources and the studies elucidating the biodistribution of exogenously administered EVs for therapeutic purposes

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This page is a summary of: Towards Therapeutic Delivery of Extracellular Vesicles: Strategies forIn VivoTracking and Biodistribution Analysis, Stem Cells International, January 2016, Hindawi Publishing Corporation,
DOI: 10.1155/2016/5029619.
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