What is it about?
Corticosteroids are used to treat a variety of diseases like bronchial asthma. However, long-term corticosteroids have a gastric ulcerogenic potential. Montelukast (MTK) and Nigella sativa oil (NSO) are used in treatment of bronchial asthma. Previous studies showed that MTK and NSO had gastroprotective effects in other models of gastric ulcer.
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Why is it important?
Corticosteroids are used to treat a variety of diseases like bronchial asthma. However, long-term corticosteroids have a gastric ulcerogenic potential. Montelukast (MTK) and Nigella sativa oil (NSO) are used in treatment of bronchial asthma. Previous studies showed that MTK and NSO had gastroprotective effects in other models of gastric ulcer.
Perspectives
We could conclude that administration of either MTK or NSO or both with DXM counteracts DXM-induced gastric lesions. KEYWORDS:
sherief Abd-Elsalam
Tanta University
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This page is a summary of: Gastroprotective effects of montelukast and Nigella sativa oil against corticosteroid-induced gastric damage: they are much more than antiasthmatic drugs, Canadian Journal of Physiology and Pharmacology, June 2017, Canadian Science Publishing,
DOI: 10.1139/cjpp-2016-0374.
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