Effect modification of the association between total cigarette smoking and ALS risk by intensity, duration and time-since-quitting: Euro-MOTOR

What is it about?

Pooled analysis of case-control studies from three European countries provides further support for the previously reported association between smoking and ALS. ALS risk among smokers decreased with increasing time-since-quitting smoking. Cigarette pack-years may not fully capture the effect of complex smoking patterns on disease risk. Further identification of time-varying predictors of risk could provide insights into the dynamics of smoking-induced ALS.

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