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This article includes an extensive review of the pathological findings in periprosthetic tissue specimens excised from patients with failed MoM prostheses. This work led to the development of the Natu score for ALVAL.

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This page is a summary of: Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties, Journal of Clinical Pathology, March 2012, BMJ,
DOI: 10.1136/jclinpath-2011-200398.
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