Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis: protocol for a randomised, double-blind, placebo-controlled trial

What is it about?

In a clinical trial we aim to test the efficacy of atorvastatin in patients with liver cirrhosis. Atorvastatin is a cholesterol lowering drug, but is also has anti-inflammatory effects, and it may improve survival in cirrhosis. The mechanism is unclear. In a randomized trial with 162 patients treated with atorvastatin or placebo for 18 months we aim to investigate the effects on survival and disease progression, and the effects of atorvastatin on the liver cell function.

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