What is it about?
The study demonstrates the role of ergosterol biosynthesis in regulating various cellular processes.
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Why is it important?
Ergosterol is an important component in the fungal cell membrane. Various anti-fungals target the ergosterol biosynthesis and hence it is important to study the physiological characteristics of ergosterol biosynthesis in yeast. This study highlights the important enzymes in the ergosterol pathway that may be used as future drug targets.
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This page is a summary of: Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility inSaccharomyces cerevisiae, mBio, July 2018, ASM Journals,
DOI: 10.1128/mbio.01291-18.
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