Thinking Globally, Acting Locally: Harnessing the Immune System to Deal with Recalcitrant Pathogens

What is it about?

In this Opinion article, I draw attention to novel approaches for enhancing host immunity to pathogens that are different from traditional vaccines. Recent advances in comprehending how pathogens manipulate host immune systems for their own advantage reveal potential strategies for counter-manipulation that are especially amenable to local application at mucosal sites of infection.

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