Upolu and Aransas Bay virus are novel orthomyxoviruses

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Why is it important?

Upolu virus (UPOV) and Aransas Bay virus (ABV) are shown to be orthomyxoviruses instead of bunyaviruses as previously thought. Genetic characterization and adequate classification of agents is paramount in this molecular age to devise appropriate surveillance and diagnostics. Although closer to Thogoto virus by sequence, UPOV and ABV differ in their coding potential, resembling more Dhori virus. Our findings enable further studies into the evolution and pathogenicity of orthomyxoviruses.