What is it about?
Rubella virus (RuV) causes a systemic infection and the transplacental fetal infection causes congenital rubella syndrome. RuV binds to cells via a direct interaction between the RuV surface glycoprotein spike E1 protein and sphingomyelin/cholesterol-enriched host cell membranes.
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This page is a summary of: Both Sphingomyelin and Cholesterol in the Host Cell Membrane Are Essential for Rubella Virus Entry, Journal of Virology, October 2017, ASM Journals,
DOI: 10.1128/jvi.01130-17.
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