Helicobacter pylori outer membrane proteins

What is it about?

This publication uses multiple proteomic methods to identify proteins localized on the surface of Helicobacter pylori. In addition, the manuscript identifies domains of surface-exposed proteins that are susceptible to proteinase K digestion, thereby providing information about the cell surface topology of these proteins.

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Why is it important?

Thus far there have been relatively few experimental efforts to identify proteins localized on the surface of H. pylori, and very little is known about the cell surface topology of these proteins. This publication identifies proteins that meet multiple criteria for surface-exposed outer membrane localization and also provides information about the cell surface topology of these proteins.

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