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This was one of the first studies to establish a complete understanding of the crossover/non-crossover decision during meiosis. We show that the FANCM-orthologue of S. pombe, Fml1, directs processing of late recombination intermediates exclusively into non-crossovers in competition with the Mus81-Eme1 endonuclease which mainly delivers crossover events.
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This page is a summary of: The Fission Yeast FANCM Ortholog Directs Non-Crossover Recombination During Meiosis, Science, June 2012, American Association for the Advancement of Science,
DOI: 10.1126/science.1220111.
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