Ionic channels and insulin secretion in pancreatic beta cells

What is it about?

This review describes the structure and function of some of the cell-membrane proteins. It also explains how these proteins facilitate insulin release by regulating electrical issues in a speciffic type of cells in the pancreas. Finally, it mentions how these proteins could be studied and modulated in diabetes by drugs or hormones.

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Why is it important?

The knowledge about the function and modulation of these proteins could be important to understand deffects that produce diseases such as diabetes or to propose new treatments or therapeutic strategies.