What is it about?
The severity of a stroke alters the extracellular vesicles released by brain cells, modifying their contents and affecting the cells of the brain's blood vessels. These changes could serve as biomarkers and help predict the progression and severity of the stroke.
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Why is it important?
The importance of this topic lies in its contribution to understanding how the brain communicates and responds to damage after a stroke. Extracellular vesicles could serve as biomarkers to detect stroke severity, predict its progression, and evaluate treatment response.
Perspectives
understanding how these vesicles affect brain blood vessel cells opens the possibility of developing therapies that protect the blood-brain barrier and reduce secondary damage.
MD Eduardo Lopez
Universidad Catolica de la Santisima Concepcion
Read the Original
This page is a summary of: Stroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells, The Journal of Physiology, January 2025, Wiley,
DOI: 10.1113/jp285907.
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