YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance

What is it about?

The immune function of Arabidopsis YDA MAP3K described here represents an example of the dual function of plant MAP3K in transducing developmental cues and environmental signals (e.g. pathogen infection) into cellular responses. We demonstrate that YDA functions downstream ERECTA receptor kinase regulating both immunity and stomatal patterning, further suggesting that plants might have evolutionarily co-opted the ER-YDA developmental pathway to generate a novel immune surveillance system linked to stomata development, since these apertures are pathogen entry points. The activation of YDA leads to the up-regulation of non-canonical immune responses and the alteration of plant cell wall integrity, which result in broad-spectrum disease resistance to pathogens with different colonization modes.

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