High‐throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and underlines a tailored response to different osmotic stressors

What is it about?

Staphylococcus aureus is an important opportunistic bacterial pathogen that can cause a variety of diseases as well as food poisoning in humans. One characteristic of S. aureus is its ability to grow in the presence of a very high salt concentration, conditions under which other bacteria are unable to survive. This salt tolerance also allows S. aureus to thrive in niches such as the human nares, skin and certain food products, and as such is important for its virulence. As part of our work, we investigated how Staphylococcus aureus responds to long term salt stress.

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