What is it about?
In this study author, determined that L-isoleucine induces defensins in a model of experimental tuberculosis and that the expression of these peptides correlates with low bacillary burden
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Why is it important?
this study suggests L-isoleucine as an adjuvant for tuberculosis therapy
Perspectives
It'll be important to assess an administration via for clinical trials and to use it in clinical trials
Bruno Rivas-Santiago
Instituto Mexicano del Seguro Social
Read the Original
This page is a summary of: Induction of β-defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis, Clinical & Experimental Immunology, January 2011, Wiley,
DOI: 10.1111/j.1365-2249.2010.04313.x.
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