What is it about?

In this population based study,the use of diclofenac was associated with a 35% increase in the risk of developing CDAD. This association persisted when we limited the analysis to non-hospitalized patients. No association was found between the use of any other NSAIDs and the risk of CDAD.

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Why is it important?

Diclofenac use is associated with a modest increase in the risk of CDAD. In patients at risk of CDAD, other NSAIDs could be prescribed.

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This page is a summary of: Non‐steroidal anti‐inflammatory drugs and the risk of Clostridium difficile‐associated disease, British Journal of Clinical Pharmacology, July 2012, Wiley,
DOI: 10.1111/j.1365-2125.2012.04191.x.
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