What is it about?
Newly endogenized genes, endogenous retoroviruses (ERVs), could overtake those previously functioned, if new ERVs better function such as cell fusions than those of previous ones. This successive incorporation of ERVs, termed "Baton pass hypothesis", could be found in tissues unique to mammals such as placenta.
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Why is it important?
Our hypothesis could explain mammals that could have used functions through repeated endogenization of retroviruses are those seen now.
Perspectives
I wrote the article, but unless excellent virologist and bioinfomatic scientist have contributed greatly, writing could not be possible or completed.
Kazuhiko Imakawa
Kyushu Tokai University
Read the Original
This page is a summary of: Baton pass hypothesis: successive incorporation of unconserved endogenous retroviral genes for placentation during mammalian evolution, Genes to Cells, September 2015, Wiley,
DOI: 10.1111/gtc.12278.
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