What is it about?

We explored the role of sensory pathway in pathophysiology of post-stroke oropharyngeal dysphagia in a group of 28 chronic unilateral post-stroke patients with event-related sensory-evoked potentials to pharyngeal stimulation (pSEP). We found that chronic post-stroke oropharyngeal dysphagia is associated with stroke severity and degree of leukoaraoisis. Impaired conduction and cortical integration of pharyngeal sensory inputs at stroke site are key features of chronic post-stroke patiens with dysphagia. These findings highlight the role of sensory pathways in the pathophysiology of post-stroke oropharyngeal dysphagia and offer a potential target for future treatments.

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Why is it important?

These results are important in order to better know the pathophysiology of post-stroke oropharyngeal dysphagia and offer a potential target for future treatments (sensory stimulation).

Perspectives

With these results we can confirm that the sensory pathway is a key feature associated with post-stroke OD. Thus, new studies assessing treatment adressed to increase the sensory input to recovery the swallowing function will be developed in this population of post-stroke patients with oropharyngeal dysphagia.

Professor Pere Clave
Hospital de Mataro

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This page is a summary of: Chronic post-stroke oropharyngeal dysphagia is associated with impaired cortical activation to pharyngeal sensory inputs, European Journal of Neurology, September 2017, Wiley,
DOI: 10.1111/ene.13392.
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