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Rho kinase inhibition induces bronchodilation in human airways. We show for the first time that G12 modulates rho kinase activation in human airway smooth muscle and may serve as a therapeutic target in asthma.

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This page is a summary of: Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3‐kinase‐mediated activation in a RhoA‐dependent manner, Bone Marrow Transplantation, November 2017, Wiley,
DOI: 10.1111/bph.14040.
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