Ketamine Uropathy: Management Consensus from BAUS

What is it about?

The article discusses the consensus method developed by the Female, Neurological and Urodynamic Urology Section of the British Association of Urological Surgeons (BAUS) for the assessment and management of urological complications related to the recreational use of ketamine. The article provides a comprehensive management pathway for ketamine-related urinary tract dysfunction and uropathy. The BAUS recommends initial assessment of the urinary tract with ultrasonography and renal function blood tests, and further investigation with additional imaging if abnormalities are detected. The article also mentions that the use of ketamine has increased in recent years, and its misuse can lead to urinary symptoms that can have a profoundly negative impact on quality of life.

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Why is it important?

This research is important because it addresses the issue of ketamine-related uropathy, which is a significant problem in patients who misuse the drug. Ketamine misuse can cause debilitating urinary symptoms that can lead to a profoundly negative impact on a patient's quality of life. The research provides a comprehensive management pathway for ketamine-related urinary tract dysfunction and uropathy, which can help healthcare professionals manage these patients effectively. Key Takeaways: 1. Ketamine misuse can cause urinary symptoms that can lead to a profoundly negative impact on a patient's quality of life. 2. A staging system has been adapted and modified from Wu et al. to assess the severity of ketamine-related uropathy. 3. Initial management of ketamine-related uropathy should focus on stopping ketamine use, and medications may be used to manage overactive bladder symptoms. 4. Further investigations, such as CT urogram and MAG3 renogram, may be needed to assess hydronephrosis and renal function. 5. Video-urodynamics and intravesical instillations may be used to manage ketamine-related uropathy, especially in cases where urinary tract reconstruction might be considered. 6. Regular monitoring of renal function and liver function tests is important in patients who continue to abuse ketamine. 7. Delaying definitive reconstruction for end-stage ketamine uropathy until ketamine cessation has occurred for at least 6 months is recommended. 8. Ketamine testing can be done using urine tests, which can detect ketamine use up to 14 days after use.